Clastogenicity of the Austroplenckia populnea (Celastraceae) Bark Wood Extract in Wistar Rat Bone Marrow Cells
نویسندگان
چکیده
منابع مشابه
Austroplenckia populnea (Celastraceae) on human cancer cells
In general, a plant extract contains low concentrations of active compounds and a large number of promising but undiscovered compounds [1]. A widely observed and accepted fact about the medicinal value of plants is mainly the bioactivity of the phytocomponents present in it. Although a major effort towards of the elucidation of bioactive phytochemicals is from purification of plant materials, v...
متن کاملAntiulcerogenic activity of crude extract, fractions and populnoic acid isolated from Austroplenckia populnea (Celastraceae).
Many plant crude extracts and their isolated compounds are the most attractive sources of new drugs and show promising results for the treatment of gastric ulcers. Austroplenckia populnea is commonly known as "marmelinho-do campo, mangabeira-brava, mangabarana and vime" and it has been used in folk medicine as anti-dysenteric and anti-rheumatic. Powdered bark wood (3.25 kg) was macerated with a...
متن کاملAntileishmanial, antimalarial and antimicrobial activities of the extract and isolated compounds from Austroplenckia populnea (Celastraceae).
Austroplenckia populnea (Celastraceae), known as "marmelinho do campo", is used in Brazilian folk medicine as antimicrobial, anti-inflammatory, and antitumoural agent. The aim of the present work was to evaluate the antimicrobial, antileishmanial and antimalarial activities of the crude hydroalcoholic extract of A. populnea (CHE) and some of its isolated compounds. The phytochemical study of th...
متن کاملEffect of constituents from samaras of Austroplenckia populnea (Celastraceae) on human cancer cells
BACKGROUND Aiming the continuity of the studies of Austroplenckia populnea, Brazilian species of the Celastraceae family, in the present study, it was investigated the effect of crude extracts obtained with ethanol, ethyl acetate and chloroform and two purified constituents, proanthocyanidin A and 4'-O-methylepigallocatechin, both isolated from its samaras, on cancer cell proliferation assays. ...
متن کاملEvaluation of the genotoxic potential of Austroplenckia populnea (Reiss) Lundell chloroform fraction from barkwood extract in rodent cells in vivo.
The genotoxic effect of the Austroplenckia populnea chloroform fraction from barkwood extract was tested in vivo on peripheral blood cells of Swiss mice with the comet assay (SCGE), and the clastogenic effect was investigated on peripheral blood cells of Swiss mice and bone marrow cells of Wistar rats, with the micronucleus and chromosome aberrations tests. The animals were treated by gavage wi...
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ژورنال
عنوان ژورنال: CYTOLOGIA
سال: 2005
ISSN: 0011-4545,1348-7019
DOI: 10.1508/cytologia.70.303